Tech Services - RiboNext

Transcriptomics

Translational Omics ServicesTranslatomics

Translatomics sequencing services can be used to explore protein synthesis regulation, the mechanisms by which non-coding RNAs affect translation, drug target screening, and ribosome-related disease research, providing high-quality data support for precision medicine, synthetic biology, and biopharmaceuticals.

Translatomics service (Ribosome Profiling, Ribo-seq) is a high-resolution ribosome footprinting analysis technique capable of precisely dissecting mRNA translation status, revealing post-transcriptional regulatory mechanisms, and exploring key processes such as translation initiation, elongation rate, and ribosome stalling.

Our technical services integrate an efficient experimental system with precise data analysis, and are widely applied in basic research, biomedicine, precision medicine, synthetic biology, and new drug development, providing professional support for cutting-edge life science research.

Genome SequencingGenomics

Genomic sequencing services are widely used in genetic research, population evolution analysis, disease association studies, biodiversity, and precision medicine, providing high-quality genomic data support for scientific research and clinical studies.

Genomic sequencing services provide whole genome sequencing (Whole Genome Sequencing, WGS) and related genomics research solutions, suitable for genetic information analysis of human, plant and animal, microbial, and complex population samples. Using next-generation sequencing (NGS) and third-generation sequencing (TGS) technologies, the service supports short-read (Illumina), long-read (PacBio, Nanopore), and hybrid assembly strategies to ensure high accuracy and coverage in genome sequencing.

Our technical services integrate an efficient experimental system with precise data analysis, and are widely applied in basic research, biomedicine, precision medicine, synthetic biology, and new drug development, providing professional support for cutting-edge life science research.

Transcriptomics

Transcriptome SequencingTranscriptomics

Transcriptomic sequencing services, combined with standardized data analysis processes such as gene expression quantification, alternative splicing analysis, transcription factor regulatory network construction, and pathway enrichment analysis, provide high-quality data support for gene regulation studies, disease biomarker discovery, personalized medicine, and biopharmaceuticals.

RNA-seq services provide comprehensive transcriptome-level gene expression analysis, widely used in gene function studies, cell state characterization, disease mechanism exploration, and drug development. Leveraging next-generation sequencing (NGS) technology combined with platforms such as Illumina, PacBio, and Nanopore, we offer precise and highly covered RNA sequencing solutions that support various sample types and research needs.

Our technical services integrate an efficient experimental system with precise data analysis, and are widely applied in basic research, biomedicine, precision medicine, synthetic biology, and new drug development, providing professional support for cutting-edge life science research.

EpigeneticsEpigenetics

As a core bridge connecting gene regulation and the external environment, epigenetics regulates gene expression through mechanisms like DNA methylation, histone modification, and chromatin remodeling, holding significant scientific value in cancer, development, and disease research.

NucleoSequence has a mature end-to-end management system for epigenetic projects, offering one-stop services from experimental design and technical implementation to data interpretation, covering cutting-edge areas such as tumor biomarker screening and environmental stress response. In the future, we will continue to innovate and promote the integration of epigenetic therapy with precision medicine, providing a scientific engine for tackling complex diseases. NucleoSequence is committed to becoming your best partner in epigenetic research!

Our technical services integrate an efficient experimental system with precise data analysis, and are widely applied in basic research, biomedicine, precision medicine, synthetic biology, and new drug development, providing professional support for cutting-edge life science research.

Proteomics ResearchProteomics

Services include TMT (multiplexed quantitative), Label-free (label-free), and DIA (full spectrum scanning) technologies. TMT provides precise quantification for up to 18 samples, Label-free is suitable for large sample sizes, and DIA enhances detection of low-abundance proteins, aiding in disease mechanism and biomarker research.

Proteomics is the study of all proteins expressed by an organism, tissue, or cell under specific time and conditions, including their structures, functions, interactions, and dynamic changes. It explores how diseases and drugs affect biological processes and explains the mechanisms of gene expression regulation, aiming to uncover the molecular basis of life activities and disease-related pathways.

Our technical services integrate an efficient experimental system with precise data analysis, and are widely applied in basic research, biomedicine, precision medicine, synthetic biology, and new drug development, providing professional support for cutting-edge life science research.

Cell ServicesCell Services

CRISPR gene knockout technology offers efficient and low off-target gene editing solutions, widely applied in microbial genetic manipulation, functional genomics, disease model construction, and gene therapy research, contributing to the advancement of precision medicine and biotechnology.

The CRISPR gene knockout technology utilizes CRISPR-Cas9-mediated genome editing to achieve efficient and highly specific target gene knockout, applicable to functional gene screening, regulatory mechanism studies, cell and microbial model construction, and drug development. We provide CRISPR-Cas9 gene knockout services for E. coli, yeast, and human cells, ensuring efficient gene editing and accurate validation.

Our technical services integrate an efficient experimental system with precise data analysis, and are widely applied in basic research, biomedicine, precision medicine, synthetic biology, and new drug development, providing professional support for cutting-edge life science research.

Purification ServicesPurification

Purification services ensure high purity and integrity of ribosomal, mRNA, and tRNA samples, meeting various research needs including structural elucidation, translatomics, drug screening, and synthetic biology, thus supporting cutting-edge biological research and biotechnological innovation.

We offer high-quality purification services for ribosomes, mRNA, and tRNA, suitable for studies in translational regulation, structural biology, functional genomics, and synthetic biology. Utilizing ultracentrifugation, gradient separation, affinity purification, and high-efficiency chromatography techniques, we ensure high-purity, high-activity RNA and ribosome samples to provide reliable materials for downstream experiments.

Our technical services integrate an efficient experimental system with precise data analysis, and are widely applied in basic research, biomedicine, precision medicine, synthetic biology, and new drug development, providing professional support for cutting-edge life science research.